New Roles for an Old Entity:

the Complement System

Sunday, August 13, 8:30 am - 12:00 noon

Chaired by:

Ashley Frazer-Abel, Ph.D. and Maria Alice Willrich, Ph.D.

8:30 - 9:10

Introduction to Complement System and Laboratory Testing

Maria Alice Willrich, Ph.D., Mayo Clinic

9:10 - 9:50

C3 Glomerulopathy - New Breakthroughs and Old Challenges

Joshua M.Thurman, M.D., University of Colorado School of Medicine

10:10 - 10:50

The Role of Complement in Atypical Hemolytic Uremic Syndrome

and Paroxysmal Nocturnal Hemoglobinuria

Meera Sridharan, M.D., Ph.D., Mayo Clinic

10:50 - 11:20

Complement Therapeutics: Reality and Perspectives

Ashley Frazer-Abel, Ph.D., D(ABMLI), Exsera BioLabs, University of Colorado School of Medicine

11:20 - Noon

Case Presentation and Round-Table Discussion

Moderated by Ashley Frazer-Abel, Ph.D. and Maria Willrich, Ph.D.



Updates in Autoimmunity: ANCA

Sunday, August 13, 2:00 pm - 5:00 pm

Chaired by:

M. Qasim Ansari, M.D. and Colleen J. Lewis, Ph.D., D(ABMLI)


ANCA-Associated Vasculitis: Introduction and a Case Study

Colleen J. Lewis, Ph.D., D(ABMLI), Quest Diagnostics Nichols Institute


Laboratory Methods for ANCA Detection - Extreme Diversity in Practice

M. Qasim Ansari, M.D., Cleveland Clinic Lerner College of Medicine


Update on ANCA-Associated Vasculitis

Carol Langford, M.D., MHS, Center for Vasculitis Care and Research, Cleveland Clinic


Panel Discussion and Question and Answer Session

Colleen Lewis, Ph.D., M. Qasim Ansari, M.D., and Carol Langford, M.D., MHS



Vaccination and Vaccine Response Assessment

in Primary and Acquired Immune Deficiencies

Monday, August 14, 8:30 am - 12:00 noon

Chaired by:

Vijaya Knight, M.D., Ph.D., and Roshini Abraham, Ph.D.



Challenges in PID: The Good, the Bad, the Ugly

Erwin Gelfand, M.D., National Jewish Health

9:00 - 9:30

Understanding and Assessing the Vaccination Response in Immunocompromised Patients

Pia Johanna Hauk, M.D., National Jewish Health

9:30 - 10:00

Live Attenuated Vaccines in Cellular Immune Deficiency Post Bone Marrow Transplant

Elena Hsieh, M.D., University of Colorado Denver

10:30 - 11:00

Measuring Immune Responses to Pneumococcal Vaccines

Moon Nahm, M.D., University of Alabama at Birmingham; WHO Pneumococcal Reference Laboratory; NIH Bacterial Respiratory Pathogen Reference Laboratory

11:00 - 11:30

Can the Measurement of Typhim Vi IgG Be Used to Assess the Response to

Polysaccharide Vaccines?

Antony Parker, Ph.D., The Binding Site Group

2:00 - 3:00 

Erwin Neter Award Lecture

Walking the Complement Pathways to Create a Unique Laboratory

Patricia B. Giclas, Ph.D., National Jewish Health


Aging and the Immune System

Tuesday, August 15, 8:30 am - 12:00 noon

Chaired by:

Amir A. Sadighi Akha, M.D., D.Phil. and Lisa K. Peterson, Ph.D.

8:30 - 9:10

Aging and the Immune System: An Overview

Amir A. Sadighi Akha, M.D., D.Phil., Mayo Clinic

9:10 - 10:00

Novel Pathways of Aging and Inflammation

Daniel R. Goldstein, M.D., University of Michigan Medical School

10:20 - 11:10

T Cell Aging - Mechanisms and Biomarkers

Jörg J. Goronzy, M.D., Ph.D., Stanford University School of Medicine

11:10 - noon

Aging, Inflammation and Poor B Cell Response

Bonnie B. Blomberg, Ph.D., University of Miami Miller School of Medicine



The Molecular  Revolution in the Clinical Laboratory and Beyond

Wednesday, August 16, 8:30 am - 12:00 noon

Chaired by:

Kevin Goudy, Ph.D.and Eric T. Weimer, Ph.D.

8:30 - 9:15 

Molecular Diagnostics in the Clinical Laboratory: Win, Lose or Draw

Kevin Goudy, Ph.D., CSI Laboratories

9:15 - 10:00  

Antibody Repertoire and Influenza Immunity

Ian York, DVM, M.Sc., Ph.D., Centers for Disease Control and Prevention


                                              10:30 - 11:15                                                

Clonal Tracking of Genetically Engineered Human Immune and Hematopoietic Cells

Through Integration Sites Analysis

Luca Biasco, Ph.D., Dana-Farber/Boston Children’s Cancer and Blood Disorders Center;

UCL Great Ormond Street Institute of Child Health

                                                              11:15 - Noon                                                                          

Cell-free DNA as a Transplant Rejection Biomarker

Eric T. Weimer, Ph.D., University of North Carolina at Chapel Hill School of Medicine